GPX1 monoclonal antibody, clone 42C9
产品名称： GPX1 monoclonal antibody, clone 42C9
英文名称： GPX1 monoclonal antibody, clone 42C9
产品编号： MAB0731
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against full length recombinant GPX1.
- Immunogen:
- Recombinant protein corresponding to full length human GPX1.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Concentration:
- 1 mg/mL
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Immunoprecipitation (1 ul)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- A comparative study on the hydroperoxide and thiol specificity of the glutathione peroxidase family and selenoprotein P.
Takebe G, Yarimizu J, Saito Y, Hayashi T, Nakamura H, Yodoi J, Nagasawa S, Takahashi K.J Biol Chem. 2002 Oct 25;277(43):41254-8. Epub 2002 Aug 15.
- 2.
- Reduction of thymine hydroperoxide by phospholipid hydroperoxide glutathione peroxidase and glutathione transferases.
Bao Y, Jemth P, Mannervik B, Williamson G.FEBS Lett. 1997 Jun 30;410(2-3):210-2.
- 3.
- Human placenta makes extracellular glutathione peroxidase and secretes it into maternal circulation.
Avissar N, Eisenmann C, Breen JG, Horowitz S, Miller RK, Cohen HJ.Am J Physiol. 1994 Jul;267(1 Pt 1):E68-76.
- Entrez GeneID:
- 2876
- Gene Name:
- GPX1
- Gene Alias:
- GSHPX1,MGC14399,MGC88245
- Gene Description:
- glutathione peroxidase 1
- Omim ID:
- 138320
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidase functions in the detoxification of hydrogen peroxide, and is one of the most important antioxidant enzymes in humans. This protein is one of only a few proteins known in higher vertebrates to contain selenocysteine, which occurs at the active site of glutathione peroxidase and is coded by UGA, that normally functions as a translation termination codon. In addition, this protein is characterized in a polyalanine sequence polymorphism in the N-terminal region, which includes three alleles with five, six or seven alanine (ALA) repeats in this sequence. The allele with five ALA repeats is significantly associated with breast cancer risk. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- cellular glutathione peroxidase
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