Nsg1 (NM_010942) Mouse Recombinant Protein
产品名称: Nsg1 (NM_010942) Mouse Recombinant Protein
英文名称: Nsg1 (NM_010942) Mouse Recombinant Protein
产品编号: PM48511M5
产品价格: 0
产品产地: 美国
品牌商标: Leading Biology
更新时间: null
使用范围: null
安诺伦(北京)生物科技有限公司
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产品概述:Purified recombinant protein of Mouse neuron specific gene family member 1 (Nsg1), with C-terminal MYC/DDK tag, expressed in HEK293T cells, 20ug 蛋白长度:A DNA sequence from Mouse cDNA ORF Clone, [GM31569V], encoding Mouse full-length Nsg1. 表达系统:HEK293T 种属:Mouse 标签类型:C-MYC/DDK 分子量:21.4 kDa 通用名:Nsg1 总结:Plays a role in the recycling mechanism in neurons of multiple receptors, including AMPAR, APP and L1CAM and acts at the level of early endosomes to promote sorting of receptors toward a recycling pathway (PubMed:15187090, PubMed:12070131, PubMed:21084623, PubMed:16037816). Regulates sorting and recycling of GRIA2 through interaction with GRIP1 and then contributes to the regulation of synaptic transmission and plasticity by affecting the recycling and targeting of AMPA receptors to the synapse (PubMed:16037816). Is required for faithful sorting of L1CAM to axons by facilitating trafficking from somatodendritic early endosome or the recycling endosome (By similarity). In an other hand, induces apoptosis via the activation of CASP3 in response to DNA damage (By similarity).[UniProtKB/Swiss-Prot Function] 形式:Liquid 浓度:>50 ug/mL as determined by microplate BCA method 纯度:> 80% as determined by SDS-PAGE and Coomassie blue staining 储存溶液:25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. 别名:m234; Neep21; p21