ROS1 (Human) Recombinant Protein
产品名称: ROS1 (Human) Recombinant Protein
英文名称: ROS1 (Human) Recombinant Protein
产品编号: P5637
产品价格: 0
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围: null
亚诺法生技股份有限公司(Abnova)
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- Specification
- Product Description:
- Human ROS1 (NP_002935.2, 1883 a.a. - 2347 a.a.) partial recombinant protein with GST tag expressed in baculovirus infected Sf21 cells.
- Theoretical MW (kDa):
- 79
- Form:
- Liquid
- Preparation Method:
- Baculovirus infected insect cell (Sf21) expression system
- Purification:
- Glutathione sepharose chromatography
- Purity:
- 54 % by SDS-PAGE/CBB staining
- Activity:
- The activity was measured by off-chip mobility shift assay. The enzyme was incubated with fluorecence-labeled substrate and Mg(or Mn)/ATP. The phosphorylated and unphosphorylated substrates were separated and detected by LabChip 3000. Substrate: IRS1. ATP: 100 uM.
- Storage Buffer:
- In 50 mM Tris-HCl, 150 mM NaCl, pH 7.5 (0.05% Brij35, 1 mM DTT, 10% glycerol)
- Storage Instruction:
- Store at -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 1 ug protein in SDS-PAGE
- Note:
- Result of activity analysis
-
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 6098
- Protein Accession#:
- NP_002935.2
- Gene Name:
- ROS1
- Gene Alias:
- MCF3,ROS,c-ros-1
- Gene Description:
- c-ros oncogene 1 , receptor tyrosine kinase
- Omim ID:
- 165020
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This proto-oncogene, highly-expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor. [provided by RefSeq
- Other Designations:
- OTTHUMP00000017814,OTTHUMP00000040389,proto-oncogene c-ros-1 protein,proto-oncogene tyrosine-protein kinase ROS,transmembrane tyrosine-specific protein kinase,v-ros UR2 sarcoma virus oncogene homolog 1,v-ros avian UR2 sarcoma virus oncogene homolog 1
- Related Disease
- Atherosclerosis
- Brain Ischemia
- Cardiovascular Diseases
- Cerebral Hemorrhage
- Coronary Artery Disease
- Coronary Disease
- Coronary Restenosis
- Genetic Predisposition to Disease
- Hypertension
- Kidney Failure, Chronic
- Lung Neoplasms
- Metabolic Syndrome X
- Myocardial Infarction
- Pulmonary Disease, Chronic Obstructive
- Renal Insufficiency, Chronic
- Stroke
- Tobacco Use Disorder
- Urinary Bladder Neoplasms
- Werner syndrome