XRCC5 Mouse Monoclonal Antibody-抗体-抗体-生物在线
北京索莱宝科技有限公司
XRCC5 Mouse Monoclonal Antibody

XRCC5 Mouse Monoclonal Antibody

商家询价

产品名称: XRCC5 Mouse Monoclonal Antibody

英文名称: Anti-XRCC5 Mouse Monoclonal Antibody

产品编号: K000136M

产品价格: null

产品产地: 北京市通州区马驹桥

品牌商标: solarbio

更新时间: 2025-01-15T14:01:02

使用范围: WB IF IP

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Anti-XRCC5 Monoclonal Antibody
品牌:solarbio | 货号:K000136M


英文名称 Anti-Ku80 Monoclonal Antibody
宿主 Mouse
别名 KARP-1;KARP1;KU80;Ku86;KUB2;NFIV
应用 WB IF IP
稀释比例 WB 1:1000. ICC 1:400. IP 1:100.
交叉反应 Human Monkey
蛋白分子量 86kDa
Gene ID 7520
保存 Store at -20°C. Avoid freeze / thaw cycles.
储存液 Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
纯化方法 Affinity purification
亚型 IgG1
免疫原 Purified recombinant human Ku80 protein fragments expressed in E.coli
性状 液体
Public Immunogen Range Purified recombinant human Ku80 protein fragments expressed in E.coli
Subcellular Locations Chromosome Nucleus nucleolus
Swiss Prot P13010
克隆号 8H1-C3-G10
克隆类型 Monoclonal Antibody
背景资料 The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. (provided by RefSeq, Jul 2008).